It’s a personal choice. If I was in a wheelchair and hunting animal X was on my bucket list and I had the opportunity to go for it I probably would.
I also agree with Rupe’s view that there are large preserves and then there are high fence shooting galleries. If a disability prevented me from hiking and backpacking over rough terrain should I just throw in the towel and give up? Of course not, there are viable options available to make possible an otherwise unattainable experience. I say go for it and don’t worry about what others think.